Ayahuasca & Brain Health

Healthline:

The main active ingredients in Ayahuasca — DMT and β-carbolines — have been shown to exhibit neuroprotective and neurorestorative qualities in some studies.

DMT activates the sigma-1 receptor (Sig-1R), a protein that blocks neurodegeneration and regulates the production of antioxidant compounds that help protect your brain cells.

A test-tube study indicated that DMT protected human brain cells from damage caused by lack of oxygen and increased cell survival.

Harimine, the main β-carboline in Ayahuasca, has been found to have anti-inflammatory, neuroprotective, and memory-boosting effects in test-tube and animal studies.

It has also been observed to increase levels of brain-derived neurotrophic factor (BDNF), a protein that plays an important role in nerve cell growth and promotes nerve cell survival.

Additionally, a test-tube study demonstrated that exposure to harmine increased the growth of human neural progenitor cells by over 70% in 4 days. These cells generate the growth of new neural cells in your brain.

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Success Is Goals

Brian Tracy:

Success is goals, and all else is commentary. All successful people are intensely goal oriented. They know what they want and they are focused single mindedly on achieving it, every single day.

Your ability to set goals is the master skill of success. Goals unlock your positive mind and release ideas and energy for goal attainment. Without goals, you simply drift and flow on the currents of life. With goals, you fly like an arrow, straight and true to your target.

The truth is that you probably have more natural potential than you could use if you lived one hundred lifetimes. Whatever you have accomplished up until now is only a small fraction of what is truly possible for you. One of the rules for success is this, it doesn’t matter where you’re coming from; all that matters is where you’re going. And where you are going is solely determined by yourself and your own thoughts.

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Amplify Your Strengths

Chase Jarvis, in Tools of Titans:

Everything is a remix, but what is your version of the remix? Say I have a relationship with a bunch of celebrities, so I might be able to get a photograph of them that no one else could because they were on my couch playing Playstation. The point is thinking about, ‘What is the unique mojo that I bring, and how can I try and amplify that?” Amplify your strengths rather than fix your weaknesses.

If you’re not the best person at capturing something visually, but you’re a good storyteller, you have your visual art, then you have an incredible narrative to go with it. When you go into art galleries – and I don’t have the budget for it, but I’m a classical-type guy – you’ll see stuff on the wall for $10 million, and you can’t figure out what it is. You read the plaque next to it and you’re like, ‘That’s a damn good story. I see how they’re selling these things.’

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A Happiness Exercise

Chade-Meng Tan, in Tools of Titans:

In many of my public talks, I guide a very simple 10-second exercise. I tell the audience members to each identify two human beings in the room and just think, “I wish for this person to be happy, and I wish for that person to be happy.” That is it. I remind them to not do or say anything, just think⁠—this is an entirely thinking exercise. The entire exercise is just 10 seconds’ worth of thinking.

Everybody emerges from this exercise smiling, happier than 10 seconds before. This is the joy of loving-kindness. It turns out that being on the giving end of a kind thought is rewarding in and of itself… All other things being equal, to increase your happiness, all you have to do is randomly wish for somebody else to be happy. That is all. It basically takes no time and no effort.

And:

During working hours or school hours, randomly identify two people who walk past you or who are standing or sitting around you. Secretly wish for them to be happy. Just think to yourself, “I wish for this person to be happy, and I wish for that person to be happy.” This is the entire practice. Don’t do anything; don’t say anything; just think. This is entirely a thinking exercise.

If you prefer, you can do this at any time of the day for any amount of time. You can also do it at any other place. If there is nobody present, you can bring someone to mind for the purpose of this exercise.

Tim Ferriss:

I tend to do a single 3- to 5- minute session at night, thinking of three people I want to be happy, often two current friends and one friend I haven’t seen in years.

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Always Test

Mark Lack:

Always test!!

The key to success is to test as much as possible and increase your chance of timing something just right to win big.

A lot of success is just persistence and timing. So test as much as possible while being persistent and you’ll increase the velocity of your success and “luck” factor.

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Write down your philosophy of life.

Some of my favorites from Ryan Holiday’s 32 Thoughts From a 32-Year-Old:

– You need a philosophy and you need to write it down. And re-write it and go over it regularly. Life is too hard (and too complicated) to try to wing it and expect to do the right thing.

– Try to think less about results. Just try to make contact with the ball. Give your best effort, make contact with the ball. The rest takes care of itself.

You gotta know what you want your day to look like. That’s how you build a life.

The world breaks all of us, Hemingway said, and those who won’t break, it kills. Be willing to give up. To fail. To admit you blew it. To try it a different way in the future. That’s the only way to survive…and to get better.

– The real benefit to wearing the same thing everyday (or having some set clothing rotation) is not actually the time or decision fatigue it saves you. It’s that you never go shopping. I went to maybe five stores in the last year? And one mall?

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Manifest the Emotion

Abraham-Hicks:

The point of creation is the launching and the alignment for the exhilaration that it brings. It’s all about the feeling. It’s 100%, that’s all creation, is about the feeling that it brings to you. The manifestation that matters most is the manifestation of emotion. And you have the ability to manifest the emotion before you manifest any of the actuality that you are all so eager about manifesting.

And:

“I like knowing that essentially we are all the same. We are all love looking for a place to happen. We are all clarity looking for a place to happen. That’s who we naturally innately are.”

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The Journey

Abraham-Hicks:

You can never have an unhappy journey to a happy destination. If you’re having a miserable time along the way, when you get to wherever you’re going, it’s going to be miserable when you get there. That’s a sign, you see.

But when you’re feeling good, when it’s fun, when you’re clear-minded, when you’re feeling frisky, when you want to go, when you’re just full of yourself — tuned in, tapped in, turned on! — when you feel like that, that’s when you know, you’ve managed to find that frequency, and now that Broader Perspective is helping you out.

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Edgy Goals

Steve Pavlina:

If you’re the type of person who got into trouble when you were younger, always getting punished for this and that, why are you trying to play it straight today? If you struggle to achieve relatively straightforward goals, perhaps you’re not the kind of person who can play it straight and expect to succeed. Perhaps you’re too much of a rebel for that strategy to work.

The key breakthrough was when I asked a simple question:

What can I do that feels edgy, rebellious, and fun but isn’t illegal?

What might be against the rules? What might push some boundaries? What would have some element of risk?

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